Newcastle were the big winners on another tense afternoon at the foot of the Premier League table as West Ham and Southampton suffered damaging defeats.
West Brom – the only member of the bottom three before kick-off in action – lost again, at home to Leicester.
The Magpies easily beat Southampton 3-0 thanks to two early goals from on-loan Chelsea winger Kenedy.
West Ham’s 3-0 home defeat by Burnley was marred by fans protesting.
Hundreds of supporters angrily massed just below the director’s box during the second half, while fans invaded the pitch after each Burnley goal.
The defeats mean Southampton are just a point above the relegation zone, with the Hammers two points above them.
In the lunchtime kick-off, Marcus Rashford scored twice on his first Premier League start since 26 December as Manchester United beat Liverpool 2-1 to open up a five-point gap in second place.
- Newcastle 3-0 Southampton
- West Brom 1-4 Leicester
- West Ham 0-3 Burnley
- Chelsea v Crystal Palace (17:30 GMT)
Elsewhere, Wayne Rooney had a penalty saved but Everton beat Brighton 2-0, West Brom were thumped again despite taking an early lead at home to Leicester and Huddersfield drew 0-0 with 10-man Swansea.
In the Championship, Cardiff won a sixth successive match to beat Birmingham and stay second – as well as inflicting the Blues’ eighth defeat in a row.
Birmingham remain in the relegation zone, as do Sunderland, who lost at QPR.
Fulham found a last-minute goal at Preston to extend their unbeaten run to 15 league games and go third in the table.
In the Scottish Premiership Kilmarnock extended their unbeaten run to nine matches by beating Ross County, while Partick Thistle increased the gap ahead of bottom club Ross County to four points after holding Aberdeen to a goalless draw.